Placemaking
uCity Square is a dynamic focal point of activity and engagement, thanks to the strong partnership between the Science Center, Wexford Science + Technology, Ventas, Cambridge Innovation Center (CIC), and other key stakeholders.
In 2024, the partnership welcomed new tenants, unveiled new artwork, and activated the knowledge community through amenities, activations, and anchor programs.
From behind-the-scenes tours to lively gatherings and marketplaces, 2024’s activations cemented uCity Square’s role as a hub where innovation, community, and culture intersect.
2024 Highlights
Key Takeaways
We activated the space.
The Lawn and tenant activations enriched the uCity Square experience with thriving events, community programs, and vibrant engagement.
We engaged our community.
Signature programs like Futures Without Guns and Life Science Showcases connected innovators and neighbors.
We prioritized partnerships.
Collaborations with tenants, artists, and organizations strengthened uCity Square’s ecosystem and cultural impact, driving growth and opportunity.
By the Numbers
2024 Impact
4.4M existing square feet
20 buildings
3 acres of outdoor space
200+ businesses
15k researchers, students, academics, and innovators
2024 Stories
Key Milestones at uCity Square
A PLACE WHERE IDEAS SPARK, CONNECTIONS THRIVE, AND OPPORTUNITY TAKES SHAPE.
2024 Momentum at uCity Square
New Tenants& Big Milestonesin 2024
In 2024, uCity Square continued to grow as a dynamic hub for innovation, culture, and community. From Wistar’s groundbreaking investment and Penn’s mRNA advancements to the openings of Two Locals Brewing and Corio, the neighborhood welcomed exciting new additions that enriched its ecosystem.
Wistar Institute Expands with $24M Investment
Wistar Institute is investing $24 million to establish a cutting-edge campus in uCity Square, launching its groundbreaking HIV Cure and Viral Disease Center. This expansion cements uCity Square’s reputation as a hub for transformative research and innovation.
Integral Molecular launches Cell Surface Bio
The new startup is aimed at revolutionizing the antibody reagent market and leveraging over two decades of expertise in antibody development. The new venture introduces VeRSaMAb antibodies, which are designed to deliver consistent and reliable results for researchers tackling complex protein targets in fields like oncology and immunology.
Spirovant Sciences achieves milestone for experimental cystic fibrosis treatment
uCity-based Spirovant Sciences dosed the first patient in its Phase 1/2 trial for SP-101, a novel aerosol-delivered gene therapy aimed at treating cystic fibrosis.
Penn’s mRNA Research Accelerates Post-Nobel Prize
One year after the Nobel Prize spotlighted its groundbreaking work, Penn’s mRNA research continues to thrive. The university is driving new advancements in mRNA technology, reinforcing its global leadership in scientific innovation.
Eli Lilly Passes Milestone FDA Approval for Alzheimer’s Drug
The U.S. Food and Drug Administration (FDA) approved Kisunla™, a groundbreaking Alzheimer’s treatment for adults with early symptomatic Alzheimer’s disease with confirmed amyloid pathology.
Two Locals: Philadelphia’s First Black-Owned Brewery
Two Locals Brewing has opened its doors in uCity Square, marking a historic moment as Philadelphia’s first Black-owned brewery. The space blends community, craft, and culture, becoming a lively addition to the neighborhood.
Corio: Italian-Inspired Dining Comes to uCity Square
A lease has been signed for Corio, a new Italian-inspired restaurant set to open in uCity Square. This exciting addition promises to bring elevated cuisine and a fresh dining experience to the community.
This impact would not be possible without the support of our funders.
Your support matters—it fuels our innovation ecosystem and allows us to continue to offer free programming.