Science Center

Ecosystem

Ecosystems don’t build themselves. In 2025, we leaned fully into the role of connector, catalyst, and convener.

Professional woman and man engage in conversation
Happy community crowd claps and dances outside
Male founder at table in conversation with female founder

From medtech momentum to uCity Square’s growing community hub, our strong partnerships create the conditions where collaboration becomes catalytic.

Ecosystem

Themes that Defined 2025

Ecosystem Orchestration

The Science Center doesn’t just gather stakeholders—it connects the right people at the right moment. By aligning capital, expertise, and talent, we curate the collisions that turn ideas into impact and unlock opportunity across the region and beyond.

uCity Partnership

The uCity partnership shows what happens when collaboration becomes a mindset. Shared infrastructure and shared goals bring researchers, entrepreneurs, and neighbors together, fueling a knowledge community where forward momentum feels both inclusive and inevitable.

Medtech Momentum

Medtech founders need more than a breakthrough—they need an ecosystem rich in assets. By linking startups to specialized spaces, clinical partners, investors, and expert guidance, we help promising technologies gain traction and transform healthcare delivery.

2025 Impact

uCity Square by the Numbers

uCity Square partnership:

uCity SquareScience CenterWexford Science + TechnologyVentas
Red and white circular graphic indicating uCity Square community members

4.4M

Existing square feet

15K

Researchers, students, academics, and innovators

20

Buildings

200

Businesses

“We’re building an innovation economy that includes world-class science, meaningful application, and shared economic growth.”

Tiffany Wilson, President & CEO

2025 Impact

Science Center by the Numbers

Colorful infographic breaking down trend week attendee demographics

Trend Week attendees represent the full healthcare stakeholder ecosystem.

Ecosystem

Stories that Defined 2025

2025 Ecosystem Momentum

Welcoming the World to uCity Square

3675 Market and the uCity Square community continued to attract domestic and international delegations eager to learn how the Science Center, Wexford Science & Technology, and CIC have collaborated to create a dynamic innovation ecosystem.

March

Oslo Science City

The Science Center, Wexford, and CIC welcomed a delegation of 25 public- and private-sector leaders from Norway who are guiding a major development initiative spearheaded by the Norwegian government. Their visit focused on learning how we curate tenant mixes, activate spaces, and design environments that foster collaboration and economic growth.

March

Team Pennsylvania Foundation

The Science Center welcomed Team Pennsylvania's Board of Directors, made up of 30 leaders from across the Commonwealth's public and private sectors, for a meeting and guided tour of 3675 Market Street. Team Pennsylvania is a statewide organization that serves as a trusted, neutral convener—aligning strategic public and private investments to help accelerate PA's economic growth.

April

Intergovernmental Healthcare Affordability Roundtable

The Science Center hosted Senator Hughes for an intergovernmental roundtable with over 25 federal, state, and local lawmakers and healthcare leaders from across Pennsylvania including Congressmembers Dwight Evans and Mary Gay Scanlon. The goal was to bring leaders together to discuss what federal healthcare cuts could mean for Pennsylvanians.

April

InBIA Global Conference

The Science Center, in partnership with CIC and Wexford, led an ecosystem tour of uCity Square for 70 attendees during the International Conference on Business Incubation (ICBI39). Held in Philadelphia in April 2025, the global conference convened entrepreneurial support professionals to connect, share best practices, and explore emerging trends.

May

SelectUSA Investment Summit

The Science Center welcomed 20 international health tech startup leaders from over a dozen countries for a panel discussion focused on Collaborating with Health Systems in Greater Philadelphia. The delegation was part of the SelectUSA Investment Summit spinoff tour cohosted by the Chamber of Commerce for Greater Philadelphia, Delaware Prosperity Partnership, and Choose New Jersey to spotlight the region's health tech ecosystem.

May

Career Connect Learning

The Science Center, Wexford, and CIC hosted a full day of STEM career exploration for high school students as part of the School District of Philadelphia's Dare to Dream Career Week. The event featured representatives from uCity tenant companies Nafees Innovations, Two Locals, CodedBy, and CIC and hands-on activity in the FirstHand Lab.

September

Bringing the World to PA

The Science Center, Wexford, and CIC hosted representatives from twelve countries for the "Bringing the World to Pennsylvania" tour, which introduces PA ecosystems and helps inform referrals for companies abroad interested in expanding to the U.S.

September

U.S. Senatorial Staff Visit the Science Center

Over two different visits in September, the Science Center welcomed Mikaela Witherspoon, Eastern Regional Director for U.S. Senator John Fetterman, and Chris Quinn, Southeastern Regional Director for U.S. Senator David H. McCormick. The visits included a walkthrough of the campus with a stop in the FirstHand STEM learning lab, a meeting with Founder Fellow Josh Freedman and a discussion on how the Science Center's recent activities aligned with the Senators' respective priorities.

September–October

Young Transatlantic Innovation Leaders Initiative

The Science Center hosted two Fellows as part of the Young Transatlantic Innovation Leaders Initiative Fellowship Program. The program is an opportunity for young European business professionals to expand their networks, gain perspective, and engage with the U.S. business sector to exchange innovative ideas and best practices.

December

PA House Speaker Joanna McClinton and Representative Amen Brown

Speaker McClinton and Representative Brown attended the FirstHand Showcase for students from Rhoads School and met with Science Center leadership to discuss the role we play in supporting and growing the life sciences industry in Philadelphia and beyond and to highlight our work introducing Philly students to STEM careers.

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Up next

2025 Impact Report

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